(19)

(11)

EP 0 938 565 A2

(12)

(43) Date of publication: 01.09.1999 Bulletin 1999/35 (21) Application number: 97930649.0 (22) Date of filing: 08.07.1997

(51) International Patent Classification (IPC):  A61K 39/ 02( . ) C12N 1/ 21( . ) C12N 9/ 14( . ) A61K 39/ 00( . ) A61K 39/ 112( . ) C12N 9/ 02( . ) C12N 15/ 74( . ) C12R 1/ 42( . ) (86) International application number: PCT/GB1997/001837 (87) International publication number: WO 1998/002552 (22.01.1998 Gazette 1998/03)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 11.07.1996 GB 19960014618 (71) Applicant: INSTITUTE FOR ANIMAL HEALTH LIMITED Newbury, Berkshire RG20 7NN (GB)	(72) Inventors: BARROW, Paul, Andrew Newbury Berkshire RG20 7NN (GB) TURNER, Arthur, Keith Newbury Berkshire RG20 7NN (GB) (74) Representative: O'Brien, Caroline Jane, et al  MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)