(19)
(11) EP 0 939 822 A2

(12)

(43) Date of publication:
08.09.1999 Bulletin 1999/36

(21) Application number: 97939629.0

(22) Date of filing: 27.08.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 31/ 35( . )
A61K 48/ 00( . )
A61P 37/ 00( . )
C07K 14/ 47( . )
C12N 5/ 10( . )
C12N 9/ 90( . )
A01K 67/ 027( . )
A61K 38/ 00( . )
A61P 7/ 00( . )
C07K 7/ 64( . )
C07K 14/ 715( . )
C12N 9/ 16( . )
C12N 15/ 54( . )
(86) International application number:
PCT/US1997/015153
(87) International publication number:
WO 1998/008956 (05.03.1998 Gazette 1998/09)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 27.08.1996 US 19960024666P

(71) Applicants:
  • PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Cambridge Massachusetts 02138 (US)
  • The Board of Trustees of The Leland S. Stanford Junior University
    Palo Alto, CA 94304 (US)

(72) Inventors:
  • SCHREIBER, Stuart, L.
    Boston, MA 02115 (US)
  • BELSHAW, Peter, J.
    Somerville, MA 02143 (US)
  • CRABTREE, Gerald
    Woodside, CA 94062 (US)

(74) Representative: Naismith, Robert Stewart, et al 
CRUIKSHANK & FAIRWEATHER 19 Royal Exchange Square
Glasgow, G1 3AE Scotland
Glasgow, G1 3AE Scotland (GB)

   


(54) USE OF MUTATED MACROLIDE BINDING PROTEIN FOR THE PREVENTION OF GUHD