(19)
(11) EP 0 941 080 A2

(12)

(43) Date of publication:
15.09.1999 Bulletin 1999/37

(21) Application number: 97949579.0

(22) Date of filing: 19.11.1997
(51) International Patent Classification (IPC): 
C07D 233/ 64( . )
A61K 31/ 18( . )
A61K 31/ 415( . )
A61K 31/ 42( . )
A61K 31/ 426( . )
A61K 31/ 4439( . )
A61P 3/ 10( . )
A61P 27/ 02( . )
C07D 213/ 34( . )
C07D 401/ 04( . )
A61K 31/ 10( . )
A61K 31/ 41( . )
A61K 31/ 4164( . )
A61K 31/ 425( . )
A61K 31/ 44( . )
A61P 1/ 04( . )
A61P 15/ 00( . )
A61P 35/ 04( . )
C07D 231/ 12( . )
(86) International application number:
PCT/US1997/021489
(87) International publication number:
WO 1998/022101 (28.05.1998 Gazette 1998/21)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 19.11.1996 US 19960031404P

(71) Applicant: G.D. SEARLE & CO.
Chicago IL 60680-5110 (US)

(72) Inventors:
  • MASFERRER, Jaime, L.
    Ballwin, MO 63011 (US)
  • RAZ, Amiram
    52503 Israel (IL)

(74) Representative: Beil, Hans Chr., Dr., et al 
BEIL, WOLFF & BEIL, Rechtsanwälte, Postfach 80 01 40
65901 Frankfurt
65901 Frankfurt (DE)

   


(54) METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS AS ANTI-ANGIOGENIC AGENTS