(19)

(11)

EP 0 942 744 A1

(12)

(43) Date of publication: 22.09.1999 Bulletin 1999/38 (21) Application number: 97946311.0 (22) Date of filing: 28.10.1997

(51) International Patent Classification (IPC):  A61K 38/ 29( . ) (86) International application number: PCT/US1997/019370 (87) International publication number: WO 1998/024471 (11.06.1998 Gazette 1998/23)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 05.12.1996 US 19960760853 (71) Applicant: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. F-75016 Paris (FR)	(72) Inventor: MOREAU, Jacques-Pierre Upton, MA 01568 (US) (74) Representative: Lunt, Mark George Francis, et al  Dibb Lupton Alsop Fountain Precinct Balm Green Sheffield S1 1RZ Sheffield S1 1RZ (GB)