N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS - Patent 0942923

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(11)

EP 0 942 923 A2

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(43)	Date of publication:
	22.09.1999 Bulletin 1999/38

(21)	Application number: 97950576.0

(22)	Date of filing: 20.11.1997

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International Patent Classification (IPC):

A61K 38/ 00^{( . )}
A61P 43/ 00^{( . )}
C07K 5/ 065^{( . )}

A61P 25/ 28^{( . )}
C07K 5/ 06^{( . )}

(86)	International application number:
	PCT/US1997/018704

(87)	International publication number:
	WO 1998/022493 (28.05.1998 Gazette 1998/21)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

22.11.1996 US 19960755334

(71)	Applicants:
	Elan Pharmaceuticals, Inc. South San Francisco, CA 94080 (US) ELI LILLY AND COMPANY Indianapolis, Indiana 46285 (US)

(72)	Inventors:
	AUDIA, James, E. Indianapolis, IN 46278 (US) FOLMER, Beverly, K. Newark, DE 19702 (US) JOHN, Varghese San Francisco, CA 94122 (US) LATIMER, Lee, H. Oakland, CA 94618 (US) NISSEN, Jeffrey, S. Indianapolis, IN 46268 (US) PORTER, Warren, J. Indianapolis, IN 46260 (US) THORSETT, Eugene, D. Moss Beach, CA 94038 (US) WU, Jing San Mateo, CA 94402 (US)

(74)	Representative: Adams, Nicola, et al
	Abel & Imray, 20 Red Lion Street London WC1R 4PQ London WC1R 4PQ (GB)

(54)	N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS