(19)
(11) EP 0 942 975 A1

(12)

(43) Date of publication:
22.09.1999 Bulletin 1999/38

(21) Application number: 97948270.0

(22) Date of filing: 07.11.1997
(51) International Patent Classification (IPC): 
A01K 67/ 027( . )
A61K 31/ 7105( . )
A61K 39/ 395( . )
A61P 27/ 06( . )
C12N 1/ 15( . )
C12N 1/ 21( . )
C12N 15/ 09( . )
A61K 31/ 7088( . )
A61K 38/ 00( . )
A61K 48/ 00( . )
C07K 14/ 47( . )
C12N 1/ 19( . )
C12N 5/ 10( . )
C12N 15/ 12( . )
(86) International application number:
PCT/US1997/020702
(87) International publication number:
WO 1998/020131 (14.05.1998 Gazette 1998/19)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 08.11.1996 US 19960748479
30.01.1997 US 19970791347
21.03.1997 US 19970822999

(71) Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
Iowa City, IA 52242-5000 (US)

(72) Inventors:
  • STONE, Edwin, M.
    Iowa City, IA 52245 (US)
  • SHEFFIELD, Val
    Coralville, IA 52240 (US)
  • ALWARD, Wallace, L., M.
    Iowa City, IA 52245 (US)

(74) Representative: Naismith, Robert Stewart, et al 
CRUIKSHANK & FAIRWEATHER 19 Royal Exchange Square
Glasgow, G1 3AE Scotland
Glasgow, G1 3AE Scotland (GB)

   


(54) GLAUCOMA-ASSOCIATED PROTEIN AND CORRESPONDING NUCLEIC ACID AND THEIR THERAPEUTIC AND DIAGNOSTIC USES