(19)
(11) EP 0 944 395 A1

(12)

(43) Date of publication:
29.09.1999 Bulletin 1999/39

(21) Application number: 97948458.0

(22) Date of filing: 19.11.1997
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 27/ 02( . )
A61P 43/ 00( . )
A61K 38/ 20( . )
A61P 37/ 06( . )
(86) International application number:
PCT/US1997/021393
(87) International publication number:
WO 1998/022130 (28.05.1998 Gazette 1998/21)
(84) Designated Contracting States:
AT BE CH DE ES FR GB IE IT LI NL SE

(30) Priority: 19.11.1996 US 19960752075
19.11.1996 US 19960077186P

(71) Applicant: THE SCHEPENS EYE RESEARCH INSTITUTE, INC.
Boston, MA 02114 (US)

(72) Inventor:
  • DANA, M., Reza
    Cambridge, MA 02138 (US)

(74) Representative: Portal, Gérard, et al 
Cabinet Beau de Loménie 158, rue de l'Université
75340 Paris Cédex 07
75340 Paris Cédex 07 (FR)

   


(54) LOCAL USE OF IL-1RA IN CORNEAL TRANSPLANT REJECTION OR DISORDERS OF THE EYE