(19)

(11)

EP 0 946 092 A1

(12)

(43) Date of publication: 06.10.1999 Bulletin 1999/40 (21) Application number: 97949380.0 (22) Date of filing: 21.11.1997

(51) International Patent Classification (IPC):  A01N 25/ 04( . ) A01N 37/ 18( . ) A61K 8/ 81( . ) A01N 25/ 24( . ) A61K 8/ 42( . ) A61Q 17/ 02( . ) (86) International application number: PCT/US1997/020358 (87) International publication number: WO 1998/023150 (04.06.1998 Gazette 1998/22)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: LT LV RO (30) Priority: 26.11.1996 US 19960756736 (71) Applicant: Elan Pharmaceuticals, Inc. South San Francisco, CA 94080 (US)	(72) Inventor: ROSS, Jamie, S. Putnam, CT 06260 (US) (74) Representative: von Kreisler, Alek, Dipl.-Chem., et al  Patentanwälte, von Kreisler-Selting-Werner, Bahnhofsvorplatz 1 (Deichmannhaus) 50667 Köln 50667 Köln (DE)