(19)
(11) EP 0 946 164 A1

(12)

(43) Date of publication:
06.10.1999 Bulletin 1999/40

(21) Application number: 97913775.0

(22) Date of filing: 27.10.1997
(51) International Patent Classification (IPC): 
A61K 31/ 18( . )
A61K 31/ 195( . )
A61K 31/ 4375( . )
A61K 31/ 505( . )
A61P 9/ 10( . )
A61P 27/ 02( . )
A61P 35/ 00( . )
C07D 213/ 73( . )
C07D 239/ 12( . )
C07D 239/ 42( . )
A61K 31/ 192( . )
A61K 31/ 437( . )
A61K 31/ 44( . )
A61P 9/ 00( . )
A61P 19/ 10( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07D 213/ 74( . )
C07D 239/ 14( . )
C07D 471/ 04( . )
(86) International application number:
PCT/US1997/019349
(87) International publication number:
WO 1998/018461 (07.05.1998 Gazette 1998/18)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 30.10.1996 US 19960029223P
18.12.1996 GB 19960026308

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • DUGGAN, Mark, E.
    Rahway, NJ 07065 (US)
  • HARTMAN, George, D.
    Rahway, NJ 07065 (US)
  • HOFFMAN, William, F.
    Rahway, NJ 07065 (US)
  • IHLE, Nathan, C.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James, et al 
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) INTEGRIN ANTAGONISTS