(19)
(11) EP 0 946 718 A1

(12)

(43) Date of publication:
06.10.1999 Bulletin 1999/40

(21) Application number: 97954318.0

(22) Date of filing: 20.12.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
C12N 5/ 10( . )
C12N 15/ 90( . )
C12R 1/ 92( . )
A61K 47/ 48( . )
C12N 9/ 00( . )
A61K 48/ 00( . )
(86) International application number:
PCT/US1997/024236
(87) International publication number:
WO 1998/028417 (02.07.1998 Gazette 1998/26)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 23.12.1996 US 19960033816

(71) Applicant: Gene-Cell
Houston, TX 77058 (US)

(72) Inventors:
  • DAVIS, Brian
    League City, TX 77573 (US)
  • YAO, Aqoing
    Galveston, TX 77550 (US)

(74) Representative: Wilkinson, Stephen John 
Stevens, Hewlett & Perkins 1 St. Augustine's Place
Bristol BS1 4UD
Bristol BS1 4UD (GB)

   


(54) NUCLEIC ACID CONSTRUCTS AND USES THEREOF FOR DIRECT NUCLEIC ACID INCORPORATION INTO CELLS