HSV/AAV HYBRID AMPLICON VECTORS - Patent 0946733

(19)

(11)

EP 0 946 733 A1

(12)

(43)	Date of publication:
	06.10.1999 Bulletin 1999/40

(21)	Application number: 97946914.0

(22)	Date of filing: 12.11.1997

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 31/ 711^{( . )}
A61K 38/ 00^{( . )}
A61K 45/ 00^{( . )}
A61P 21/ 04^{( . )}
A61P 25/ 28^{( . )}
C07K 14/ 015^{( . )}
C12P 21/ 02^{( . )}

A61K 31/ 54^{( . )}
A61K 35/ 76^{( . )}
A61K 38/ 44^{( . )}
A61K 48/ 00^{( . )}
A61P 25/ 16^{( . )}
A61P 35/ 00^{( . )}
C12N 15/ 869^{( . )}

(86)	International application number:
	PCT/US1997/020422

(87)	International publication number:
	WO 1998/021345 (22.05.1998 Gazette 1998/20)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

12.11.1996 US 19960747919

(71)	Applicants:
	THE GENERAL HOSPITAL CORPORATION Boston, MA 02114 (US) Eunice Kennedy Shriver Center for Mental Retardation, Inc. Waltham, MA 02154-6319 (US)

(72)	Inventors:
	BREAKEFIELD, Xandra, O. Newton, MA 02159 (US) JACOBY, David, R. Boston, MA 02115 (US) SMITH, Frances, I. Lincoln, MA 01773 (US)

(74)	Representative: Nicholls, Kathryn Margaret, et al
	MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)

(54)	HSV/AAV HYBRID AMPLICON VECTORS