JUNCTIONAL ADHESION MOLECULE (JAM), A TRANSMEMBRANE PROTEIN OF TIGHT JUNCTIONS - Patent 0948621

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(11)

EP 0 948 621 A1

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(43)	Date of publication:
	13.10.1999 Bulletin 1999/41

(21)	Application number: 97952843.0

(22)	Date of filing: 01.12.1997

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International Patent Classification (IPC):

A01K 67/ 027^{( . )}
A61K 38/ 00^{( . )}
A61K 39/ 395^{( . )}
A61P 35/ 00^{( . )}
C07K 14/ 705^{( . )}
C12N 15/ 09^{( . )}
C12P 21/ 02^{( . )}
G01N 33/ 53^{( . )}
C12R 1/ 91^{( . )}

A61K 35/ 76^{( . )}
A61K 39/ 39^{( . )}
A61K 48/ 00^{( . )}
C07K 14/ 47^{( . )}
C07K 16/ 18^{( . )}
C12N 15/ 12^{( . )}
C12P 21/ 08^{( . )}
A61K 39/ 00^{( . )}

(86)	International application number:
	PCT/EP1997/006723

(87)	International publication number:
	WO 1998/024897 (11.06.1998 Gazette 1998/23)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IE IT LI NL SE

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Priority:

04.12.1996 SE 19960004470

(71)	Applicant: F. HOFFMANN-LA ROCHE AG
	4070 Basel (CH)

(72)	Inventors:
	DEJANA, Elisabetta I-20146 Milano (IT) MARTIN PADURA, Ines I-20146 Milano (IT) SIMMONS, David Headington Oxford 0X3 9JY (GB) WILLIAMS, Lisa Headington Oxford 0X3 9EW (GB)

(74)	Representative: Wächter, Dieter Ernst, Dr., et al
	F.Hoffmann-La Roche AG Patent Department (PLP), 124 Grenzacherstrasse 4070 Basel 4070 Basel (CH)

(54)	JUNCTIONAL ADHESION MOLECULE (JAM), A TRANSMEMBRANE PROTEIN OF TIGHT JUNCTIONS