(19)

(11)

EP 0 951 548 A1

(12)

(43) Date of publication: 27.10.1999 Bulletin 1999/43 (21) Application number: 97954903.0 (22) Date of filing: 12.12.1997

(51) International Patent Classification (IPC):  C07K 14/ 705( . ) G01N 33/ 68( . ) C12N 15/ 12( . ) (86) International application number: PCT/EP1997/007339 (87) International publication number: WO 1998/026065 (18.06.1998 Gazette 1998/24)

(84) Designated Contracting States: BE CH DE FR GB LI (30) Priority: 12.12.1996 EP 19960402719 (71) Applicant: Vetigen 75015 Paris (FR)	(72) Inventors: Lenzen, Gerlinde 75015 Paris (FR) Strosberg, Arthur Donny 75015 Paris (FR) Sugasawa, Toshinari Osaka 569 (JP) Morooka, Shigeaki Hyogo 666-01 (JP) (74) Representative: Mouget-Goniot, Claire, et al  Cabinet Orès, 6, Avenue de Messine 75008 Paris 75008 Paris (FR)