(19)
(11) EP 0 952 845 A1

(12)

(43) Date of publication:
03.11.1999 Bulletin 1999/44

(21) Application number: 97953356.0

(22) Date of filing: 19.12.1997
(51) International Patent Classification (IPC): 
A61K 35/ 34( . )
A61K 38/ 18( . )
A61P 9/ 02( . )
C07K 14/ 47( . )
A61K 35/ 12( . )
A61K 38/ 00( . )
A61K 45/ 00( . )
A61P 9/ 04( . )
C12N 5/ 077( . )
(86) International application number:
PCT/US1997/023611
(87) International publication number:
WO 1998/027995 (02.07.1998 Gazette 1998/26)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 20.12.1996 US 19960033145P

(71) Applicant: CREATIVE BIOMOLECULES, INC.
Hopkinton, MA 01748 (US)

(72) Inventors:
  • COHEN, Charles, M.
    Weston, MA 02193 (US)
  • SAMPATH, Kuber, T.
    Hollison, MA 01746 (US)

(74) Representative: Schlich, George William, et al 
Mathys & Squire 100 Gray's Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) TREATMENT OF MAMMALIAN MYOCARDIUM WITH MORPHOGEN LOCALLY, OR WITH MORPHOGENICALLY-TREATED MYOGENIC PRECURSOR CELLS