(19)

(11)

EP 0 954 534 A1

(12)

(43) Date of publication: 10.11.1999 Bulletin 1999/45 (21) Application number: 97930259.0 (22) Date of filing: 18.07.1997

(51) International Patent Classification (IPC):  A61K 39/ 395( . ) A61P 37/ 02( . ) C07K 16/ 00( . ) A61L 2/ 00( . ) C07K 1/ 14( . ) (86) International application number: PCT/AU1997/000454 (87) International publication number: WO 1998/003550 (29.01.1998 Gazette 1998/04)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 18.07.1996 AU 1996PO01112 05.03.1997 AU 1997PO05462 (71) Applicant: CSL LIMITED Parkville, VIC 3052 (AU)	(72) Inventors: BERTOLINI, Joseph Ashburton, VIC 3147 (AU) COPPOLA, Germano Croydon, VIC 3136 (AU) DAVIES, Jeffrey, Raymond Ivanhoe, VIC 3079 (AU) (74) Representative: Sheard, Andrew Gregory, et al  Kilburn & Strode 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)