(19)

(11)

EP 0 957 888 A1

(12)

(43) Date of publication: 24.11.1999 Bulletin 1999/47 (21) Application number: 97938195.0 (22) Date of filing: 07.08.1997

(51) International Patent Classification (IPC):  C12N 1/ 16( . ) A61K 8/ 20( . ) A61K 8/ 26( . ) A61K 8/ 34( . ) A61K 8/ 37( . ) A61K 8/ 44( . ) A61K 8/ 89( . ) A61K 8/ 92( . ) A61K 8/ 98( . ) A61Q 1/ 00( . ) A61Q 1/ 06( . ) A61K 8/ 00( . ) A61K 8/ 25( . ) A61K 8/ 31( . ) A61K 8/ 36( . ) A61K 8/ 40( . ) A61K 8/ 65( . ) A61K 8/ 891( . ) A61K 8/ 97( . ) A61K 8/ 99( . ) A61Q 1/ 04( . ) (86) International application number: PCT/US1997/013997 (87) International publication number: WO 1998/008484 (05.03.1998 Gazette 1998/09)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 30.08.1996 US 19960705779 (71) Applicant: AVON PRODUCTS, INC. New York, NY 10020-1196 (US)	(72) Inventors: SCANCARELLA, Neil Wyckoff, NJ 07481 (US) PAHLCK, Harold Waldwick, NJ 07463 (US) RAOUF, Maha Franklin Lakes, NJ 07417 (US) (74) Representative: Dr. Weitzel & Partner  Friedenstrasse 10 89522 Heidenheim 89522 Heidenheim (DE)