(19)
(11) EP 0 964 617 A1

(12)

(43) Date of publication:
22.12.1999 Bulletin 1999/51

(21) Application number: 98953264.0

(22) Date of filing: 06.10.1998
(51) International Patent Classification (IPC): 
G01N 33/ 566( . )
A61K 45/ 00( . )
C07K 14/ 00( . )
C07K 14/ 025( . )
G06F 17/ 30( . )
A61K 38/ 00( . )
A61P 31/ 20( . )
C07K 14/ 02( . )
G01N 33/ 569( . )
(86) International application number:
PCT/US1998/020991
(87) International publication number:
WO 1999/017616 (15.04.1999 Gazette 1999/15)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.10.1997 US 19970061295P

(71) Applicant: NEW ENGLAND MEDICAL CENTER HOSPITALS, INC.
Boston, MA 02111 (US)

(72) Inventors:
  • ANDROPHY, Elliot, J.
    Natick, MA 01760 (US)
  • BALEJA, James, D.
    Boston, MA 02116 (US)
  • CHEN, Jason, J.
    Boston, MA 02215 (US)

(74) Representative: Ruffles, Graham Keith 
MARKS & CLERK, 57-60 Lincoln's Inn Fields
London WC2A 3LS
London WC2A 3LS (GB)

   


(54) STRUCTURE-BASED RATIONAL DESIGN OF COMPOUNDS TO INHIBIT PAPILLOMAVIRUS INFECTION