(19)

(11)

EP 0 967 965 A1

(12)

(43) Date of publication: 05.01.2000 Bulletin 2000/01 (21) Application number: 97934943.8 (22) Date of filing: 24.07.1997

(51) International Patent Classification (IPC)7: A61K 7/16 (86) International application number: PCT/US9712/208 (87) International publication number: WO 9804/234 (05.02.1998 Gazette 1998/05)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 25.07.1996 US 22705 P (71) Applicant: WHITEHILL ORAL TECHNOLOGIES INC. Chadds Ford, PA 19317 (US)	(72) Inventor: HILL, Ira, D. Locust, NJ 07760 (US) (74) Representative: Ruffles, Graham Keith  MARKS & CLERK,57-60 Lincoln's Inn Fields London WC2A 3LS London WC2A 3LS (GB)