(19)

(11)

EP 0 969 794 A2

(12)

(88) Date of publication A3: 03.12.1998 (43) Date of publication: 12.01.2000 Bulletin 2000/02 (21) Application number: 97908931.5 (22) Date of filing: 10.03.1997

(51) International Patent Classification (IPC)7: A61K 7/06 (86) International application number: PCT/US9703/564 (87) International publication number: WO 9840/046 (17.09.1998 Gazette 1998/37)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: MITSUMATSU, Arata AshiyaHyogo 659 (JP) NAKAMURA, Kiichiro Higashinada-kuKobe 658 (JP) (74) Representative: Woof, Victoria et al Procter & GambleTechnical Centers Limited,Lovett House,Lovett Road Staines, Middlesex TW18 3AZ Staines, Middlesex TW18 3AZ (GB)