(19)

(11)

EP 0 969 831 A1

(12)

(43) Date of publication: 12.01.2000 Bulletin 2000/02 (21) Application number: 98920488.8 (22) Date of filing: 24.03.1998

(51) International Patent Classification (IPC)7: A61K 31/40, A61K 9/00, A61K 47/48 (86) International application number: PCT/EP9801/783 (87) International publication number: WO 9842/333 (01.10.1998 Gazette 1998/39)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 26.03.1997 EP 97200920 (71) Applicant: Merkus, Franciscus Wilhelmus Henricus Maria B-2460 Kasterlee (BE)	(72) Inventor: Merkus, Franciscus Wilhelmus Henricus Maria B-2460 Kasterlee (BE) (74) Representative: Jump, Timothy John Simon  Venner Shipley & Co.20 Little Britain London EC1A 7DH London EC1A 7DH (GB)