(19)

(11)

EP 0 969 872 A2

(12)

(88) Date of publication A3: 11.02.1999 (43) Date of publication: 12.01.2000 Bulletin 2000/02 (21) Application number: 98907366.3 (22) Date of filing: 05.02.1998

(51) International Patent Classification (IPC)7: A61K 47/48 (86) International application number: PCT/US9802/103 (87) International publication number: WO 9833/528 (06.08.1998 Gazette 1998/31)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 05.02.1997 US 795925 (71) Applicant: BIOTRANSPLANT, INC Charlestown, MA 02129 (US)	(72) Inventor: THALL, Aron Beverly, MA 01915 (US) (74) Representative: Vossius, Volker, Dr. et al Dr. Volker Vossius,Patentanwaltskanzlei - Rechtsanwaltskanzlei,Holbeinstrasse 5 81679 München 81679 München (DE)