(19)

(11)

EP 0 971 883 A1

(12)

(43) Date of publication: 19.01.2000 Bulletin 2000/03 (21) Application number: 98912117.3 (22) Date of filing: 30.03.1998

(51) International Patent Classification (IPC)7: C07C 235/00, C07C 237/00, C07C 239/00 (86) International application number: PCT/US9806/214 (87) International publication number: WO 9847/861 (29.10.1998 Gazette 1998/43)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 24.04.1997 US 44186 P (71) Applicant: Bristol-Myers Squibb Company Wallingford, CT 06492-7660 (US)	(72) Inventors: ZUSI, Fred, C. Hamden, CT 06514 (US) RECZEK, Peter, R. E. Amherst, NY 14051 (US) OSTROWSKI, Jacek Getzville, NY 14068 (US) (74) Representative: Modiano, Guido, Dr.-Ing. et al Modiano, Josif, Pisanty & Staub,Baaderstrasse 3 80469 München 80469 München (DE)