(19)
(11) EP 0 971 891 A1

(12)

(43) Date of publication:
19.01.2000 Bulletin 2000/03

(21) Application number: 98902807.1

(22) Date of filing: 16.01.1998
(51) International Patent Classification (IPC)7C07D 211/80, C07D 401/02, A61K 31/44
(86) International application number:
PCT/US9800/875
(87) International publication number:
WO 9831/670 (23.07.1998 Gazette 1998/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 22.01.1997 US 36149 P
28.02.1997 GB 9704209

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • SANDERSON, Philip, E.
    Rahway, NJ 07065 (US)
  • LYLE, Terry, A.
    Rahway, NJ 07065 (US)
  • COBURN, Craig
    Rahway, NJ 07065 (US)

(74) Representative: Horgan, James Michael Frederic 
Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) THROMBIN INHIBITORS