(19)

(11)

EP 0 973 738 A1

(12)

(43) Date of publication: 26.01.2000 Bulletin 2000/04 (21) Application number: 98906859.8 (22) Date of filing: 06.03.1998

(51) International Patent Classification (IPC)7: C07D 207/12, A61K 31/40 (86) International application number: PCT/DK9800/084 (87) International publication number: WO 9840/353 (17.09.1998 Gazette 1998/37)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.03.1997 DK 24897 (71) Applicant: NOVO NORDISK A/S 2880 Bagsvaerd (DK)	(72) Inventors: KRISTIANSEN, Marit DK-2860 Soborg (DK) JAKOBSEN, Palle DK-3500 Vaerlose (DK) LUNDBECK, Jane, Marie DK-2600 Glostrup (DK)