(19)

(11)

EP 0 973 864 A1

(12)

(43) Date of publication: 26.01.2000 Bulletin 2000/04 (21) Application number: 98900912.1 (22) Date of filing: 19.01.1998

(51) International Patent Classification (IPC)7: C12N 1/21 (86) International application number: PCT/GB9800/156 (87) International publication number: WO 9831/786 (23.07.1998 Gazette 1998/29)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 17.01.1997 GB 9700939 (71) Applicant: MICROBIAL TECHNICS LIMITED Cambridge, CB2 1QA (GB)	(72) Inventors: WELLS, Jeremy, MarkActinova Ltd. WatebeechCambridge CB5 9PB (GB) LE PAGE, Richard, William, FallaUniversity of Cambridge CB2 1QP (GB) GILBERT, Christophe, François, GuyUniversity of Cambridge CB2 1QP (GB)