(19)
(11) EP 0 977 595 A1

(12)

(43) Date of publication:
09.02.2000 Bulletin 2000/06

(21) Application number: 97925747.4

(22) Date of filing: 28.05.1997
(51) International Patent Classification (IPC)7A61K 48/00, C12N 15/09, C12N 15/85
(86) International application number:
PCT/US9709/040
(87) International publication number:
WO 9745/142 (04.12.1997 Gazette 1997/52)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
RO SI

(30) Priority: 31.05.1996 US 656451

(71) Applicant: GENETIC THERAPY, INC.
Gaithersburg, MD 20878 (US)

(72) Inventors:
  • MUNSHI, Nikhil
    Little Rock, AR 72212 (US)
  • ENNIST, David, L.
    Bethesda, MD 20817 (US)
  • JACOB, William, F.
    Germantown, MD 20874 (US)
  • CHIANG, Yawen, L.
    Potomac, MD 20854 (US)

(74) Representative: Becker, Konrad et al
Novartis AGGeistiges Eigentum KonzernPatent- und Markenabteilung CHPostfach
4002 Basel
4002 Basel (CH)

   


(54) PREVENTION OF GRAFT-VERSUS-HOST DISEASE WITH T-CELLS INCLUDING POLYNUCLEOTIDES ENCODING NEGATIVE SELECTIVE MARKERS