(19)
(11) EP 0 977 743 A1

(12)

(43) Date of publication:
09.02.2000 Bulletin 2000/06

(21) Application number: 98918482.5

(22) Date of filing: 23.04.1998
(51) International Patent Classification (IPC)7C07D 277/32, A61K 31/425
(86) International application number:
PCT/US9807/942
(87) International publication number:
WO 9849/152 (05.11.1998 Gazette 1998/44)
(84) Designated Contracting States:
BE CH DE ES FR GB IT LI NL

(30) Priority: 25.04.1997 US 44906 P

(71) Applicant: Smithkline Beecham
Philadelphia, PA 19103 (US)

(72) Inventors:
  • DesJARLAIS, Renee, Louise
    St. Davids, PA 19087 (US)
  • DUFFY, Kevin, James
    Norristown, PA 19403 (US)
  • HALBERT, Stacie, Marie
    Harleysville, PA 19438 (US)
  • KEENAN, Richard, McCulloch
    Malvern, PA 19355 (US)
  • MICHAUD, Evelyne
    Norristown, PA 19401 (US)
  • THOMPSON, Scott, Kevin
    Phoenixville, PA 19460 (US)
  • VEBER, Daniel, Frank
    Ambler, PA 19002 (US)

(74) Representative: Rutter, Keith, Dr. et al
SmithKline Beecham plcCorporate Intellectual Property,Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) PROTEASE INHIBITORS