(19)
(11) EP 0 977 775 A2

(12)

(88) Date of publication A3:
05.11.1998

(43) Date of publication:
09.02.2000 Bulletin 2000/06

(21) Application number: 98906648.5

(22) Date of filing: 25.02.1998
(51) International Patent Classification (IPC)7C07K 14/00, C12Q 1/68
(86) International application number:
PCT/US9803/490
(87) International publication number:
WO 9837/092 (27.08.1998 Gazette 1998/34)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 25.02.1997 US 810153
28.02.1997 WO PCT/US97/03217

(71) Applicants:
  • THE PROCTER & GAMBLE COMPANY
    Cincinnati,Ohio 45202 (US)
  • CASE WESTERN RESERVE UNIVERSITY
    Cleveland, OH 44106-7080 (US)

(72) Inventors:
  • TINDAL, Michael, Howard
    Wyoming, OH 45215 (US)
  • HAQQI, Tariq, Mehmood
    Cleveland Heights, OH 44118 (US)

(74) Representative: Woof, Victoria et al
Procter & GambleTechnical Centers Limited,Lovett House,Lovett Road
Staines, Middlesex TW18 3AZ
Staines, Middlesex TW18 3AZ (GB)

   


(54) USE OF A NOVEL DISINTEGRIN METALLOPROTEASE, MUTANTS, FRAGMENTS AND THE LIKE