(19)
(11) EP 0 977 851 A2

(12)

(88) Date of publication A3:
18.02.1999

(43) Date of publication:
09.02.2000 Bulletin 2000/06

(21) Application number: 98918517.8

(22) Date of filing: 14.04.1998
(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/47, A61K 38/17
(86) International application number:
PCT/US9807/999
(87) International publication number:
WO 9846/757 (22.10.1998 Gazette 1998/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 15.04.1997 US 843374
13.04.1998 US 59487

(71) Applicant: GENETICS INSTITUTE, INC.
Cambridge,Massachusetts 02140 (US)

(72) Inventors:
  • JACOBS, Kenneth
    Newton, MA 02160 (US)
  • MCCOY, John, M.
    Reading, MA 01867 (US)
  • LAVALLIE, Edward, R.
    Harvard, MA 01451 (US)
  • RACIE, Lisa, A.
    Acton, MA 01720 (US)
  • MERBERG, David
    Acton, MA 01720 (US)
  • TREACY, Maurice
    Chestnut Hill, MA 02167 (US)
  • SPAULDING, Vikki
    Billeria, MA 01821 (US)
  • AGOSTINO, Michael, J.
    Andover, MA 01810 (US)

(74) Representative: Frohwitter, Bernhard, Dipl.-Ing. 
Patent- und Rechtsanwälte,Possartstrasse 20
81679 München
81679 München (DE)

   


(54) SECRETED PROTEINS AND POLYNUCLEOTIDES ENCODING THEM