(19)
(11) EP 0 979 311 A1

(12)

(43) Date of publication:
16.02.2000 Bulletin 2000/07

(21) Application number: 98920930.9

(22) Date of filing: 30.04.1998
(51) International Patent Classification (IPC)7C12Q 1/68, A61K 48/00, C07H 21/04
(86) International application number:
PCT/US9808/834
(87) International publication number:
WO 9849/350 (05.11.1998 Gazette 1998/44)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 30.04.1997 US 45288 P
05.08.1997 US 54837 P
10.11.1997 US 64996 P

(71) Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Minneapolis,Minnesota 55415-1226 (US)

(72) Inventors:
  • REGENTS OF THE UNIVERSITY OF MINNESOTA
    Minneapolis, MN 55415-1226 (US)
  • STEER, Clifford, J.
    St. Paul, MN 55116-1339 (US)
  • KREN, Betsy, T.
    Minneapolis, MN 55454 (US)
  • BANDYOPADHYAY, Paramita, T.
    Minneapolis, MN 55414 (US)

(74) Representative: Horner, Martin Grenville et al
Cruikshank & Fairweather19 Royal Exchange Square
Glasgow G1 3AEScotland
Glasgow G1 3AEScotland (GB)

   


(54) $i(IN VIVO) USE OF RECOMBINAGENIC OLIGONUCLEOBASES TO CORRECT GENETIC LESIONS IN HEPATOCYTES