(19)
(11) EP 0 980 424 A2

(12)

(88) Date of publication A3:
29.07.1999

(43) Date of publication:
23.02.2000 Bulletin 2000/08

(21) Application number: 98920299.9

(22) Date of filing: 05.05.1998
(51) International Patent Classification (IPC)7C12N 9/00
(86) International application number:
PCT/US9809/249
(87) International publication number:
WO 9850/530 (12.11.1998 Gazette 1998/45)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 09.05.1997 US 46059 P
09.06.1997 US 49002 P
03.07.1997 US 51718 P
22.08.1997 US 56808 P
02.10.1997 US 61324 P
02.10.1997 US 61321 P
05.11.1997 US 64866 P
19.12.1997 US 68212 P

(71) Applicant: RIBOZYME PHARMACEUTICALS, INC.
Boulder, CO 80301 (US)

(72) Inventors:
  • JARVIS, Thale
    Boulder, CO 80301 (US)
  • MATULIC-ADAMIC, Jasenka
    Boulder, CO 80303 (US)
  • REYNOLDS, Mark
    Lafayette, CO 80026 (US)
  • KISICH, Kevin
    Lafayette, CO 80026 (US)
  • BELLON, Laurent
    Boulder, CO 80301 (US)
  • PARRY, Tom
    Broomfield, CO 80020 (US)
  • BEIGELMAN, Leonid
    Longmont, CO 80503 (US)
  • MCSWIGGEN, James, A.
    Boulder, CO 80301 (US)
  • KARPEISKY, Alexander
    Lafayette, CO 80024 (US)
  • BURGIN, Alex
    Chula Vista, CA 91910 (US)
  • THOMPSON, James
    Boulder, CO 80301 (US)
  • WORKMAN, Christopher, T.
    Boulder, CO 80303 (US)
  • BEAUDRY, Amber
    Lafayette, CO 80026 (US)
  • SWEEDLER, David
    Louisville, CO 80027 (US)

(74) Representative: Moon, Donald Keith et al
BREWER & SONQuality HouseQuality CourtChancery Lane
London WC2A 1HT
London WC2A 1HT (GB)

   


(54) ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE