(19)

(11)

EP 0 981 603 A1

(12)

(43) Date of publication: 01.03.2000 Bulletin 2000/09 (21) Application number: 98905158.6 (22) Date of filing: 04.03.1998

(51) International Patent Classification (IPC)7: C12N 5/06, C12N 5/08, C12N 15/19, A61K 38/19, A61K 39/395, C07K 14/53, C07K 14/535, C07K 16/24, A01K 67/027 (86) International application number: PCT/AU9800/139 (87) International publication number: WO 9839/413 (11.09.1998 Gazette 1998/36)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 04.03.1997 AU PO540997 (71) Applicant: Ludwig Institute For Cancer Research Parkville, VIC 3050 (AU)	(72) Inventors: BASU, Sunanda Templestowe, VIC 3106 (AU) DUNN, Ashley RogerLudwig Institute for Cancer Res Parkville,VIC 3050 (AU) (74) Representative: Brasnett, Adrian Hugh et al Mewburn EllisYork House23 Kingsway London WC2B 6HP London WC2B 6HP (GB)