(19)

(11)

EP 0 986 362 A2

(12)

(88) Date of publication A3: 15.04.1999 (43) Date of publication: 22.03.2000 Bulletin 2000/12 (21) Application number: 98924981.8 (22) Date of filing: 29.05.1998

(51) International Patent Classification (IPC)7: A61K 6/10 (86) International application number: PCT/US9810/942 (87) International publication number: WO 9853/791 (03.12.1998 Gazette 1998/48)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 29.05.1997 US 47906 P 27.05.1998 US  (71) Applicant: DENTSPLY INTERNATIONAL, INC. York, PA 17405-0872 (US)	(72) Inventors: FIEDLER, Jurgen, Hans D-78462 Konstanz (DE) HARE, Robert, V. Georgetown, DE 19947 (US) (74) Representative: Hartz, Nikolai F., Dr. et al Wächtershäuser & Hartz,Patentanwälte,Tal 29 80331 München 80331 München (DE)