(19)

(11)

EP 0 986 760 A2

(12)

(88) Date of publication A3: 11.03.1999 (43) Date of publication: 22.03.2000 Bulletin 2000/12 (21) Application number: 98922971.1 (22) Date of filing: 26.05.1998

(51) International Patent Classification (IPC)7: G01N 33/68 (86) International application number: PCT/GB9801/520 (87) International publication number: WO 9854/575 (03.12.1998 Gazette 1998/48)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB IE IT LI NL SE (30) Priority: 27.05.1997 WO PCT/GB97/01439 (71) Applicant: University of Wales College of Medicine Cardiff CF4 4XN (GB)	(72) Inventor: MOORE, Keith Usk,Monmouthshire NP5 1RG (GB) (74) Representative: Newell, William Joseph  Wynne-Jones Laine & James,33 St Mary Street Cardiff CF10 1AF Cardiff CF10 1AF (GB)