(19)

(11)

EP 0 988 308 A1

(12)

(43) Date of publication: 29.03.2000 Bulletin 2000/13 (21) Application number: 98919394.1 (22) Date of filing: 15.05.1998

(51) International Patent Classification (IPC)7: C07H 17/08, A61K 31/70 (86) International application number: PCT/IB9800/741 (87) International publication number: WO 9856/800 (17.12.1998 Gazette 1998/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 11.06.1997 US 49349 P (71) Applicant: Pfizer Products Inc. Groton,Connecticut 06340 (US)	(72) Inventor: WU, Yong-Jin East Lyme, CT 06333 (US) (74) Representative: McMunn, Watson Palmer et al Pfizer LimitedPatents DepartmentRamsgate Road Sandwich, Kent CT13 9NJ Sandwich, Kent CT13 9NJ (GB)