(19)
(11) EP 0 989 855 A1

(12)

(43) Date of publication:
05.04.2000 Bulletin 2000/14

(21) Application number: 98922211.2

(22) Date of filing: 13.05.1998
(51) International Patent Classification (IPC)7A61K 35/28, C12N 5/02, C12N 5/08
(86) International application number:
PCT/US9809/614
(87) International publication number:
WO 9851/317 (19.11.1998 Gazette 1998/46)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 13.05.1997 US 47002

(71) Applicants:
  • Osiris Therapeutics, Inc.
    Baltimore, MD 21231-2001 (US)
  • CASE WESTERN RESERVE UNIVERSITY
    Cleveland, OH 44106-7080 (US)

(72) Inventors:
  • GOLDBERG, Victor, M.
    Gates Mills, OH 44040 (US)
  • CAPLAN, Arnold, I.
    Cleveland Heights, OH 44121 (US)
  • BARRY, Francis, P.
    Baltimore, MD 21207 (US)
  • FINK, David, J.
    Shaker Heights, OH 44120 (US)
  • MARSHAK, Daniel, R.
    Lutherville, MD 21093 (US)
  • BURNS, James, S.
    Annapolis, MD 21403 (US)

(74) Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH 
Postfach 3055
90014 Nürnberg
90014 Nürnberg (DE)

   


(54) OSTEOARTHRITIS CARTILAGE REGENERATION USING HUMAN MESENCHYMAL STEM CELLS