(19)
(11) EP 0 989 979 A1

(12)

(43) Date of publication:
05.04.2000 Bulletin 2000/14

(21) Application number: 98932717.6

(22) Date of filing: 15.06.1998
(51) International Patent Classification (IPC)7: C07D 401/04, C07D 221/16, A61K 31/55, A61K 31/435
// (C07D401/04, 221:00), C07D211:00
(86) International application number:
PCT/US9811/507
(87) International publication number:
WO 9857/948 (23.12.1998 Gazette 1998/51)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
LV RO SI

(30) Priority: 17.06.1997 US 877049

(71) Applicant: SCHERING CORPORATION
KenilworthNew Jersey 07033 (US)

(72) Inventors:
  • REMISZEWSKI, Stacy
    Washington Township, NJ 07675 (US)
  • MALLAMS, Alan, K.
    Hackettstown, NJ 07840 (US)

(74) Representative: Ritter, Stephen David et al
Mathys & Squire100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) NOVEL N-SUBSTITUTED UREA INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE