(19)
(11) EP 0 989 980 A1

(12)

(43) Date of publication:
05.04.2000 Bulletin 2000/14

(21) Application number: 98932718.4

(22) Date of filing: 15.06.1998
(51) International Patent Classification (IPC)7: C07D 401/04, A61K 31/55, A61K 31/435, A61K 31/445, C07D 221/16, C07D 401/14
// (C07D401/14, 333:00, 261:00), C07D221:00,(C07D401/04, 233:00), C07D221:00
(86) International application number:
PCT/US9811/508
(87) International publication number:
WO 9857/949 (23.12.1998 Gazette 1998/51)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
LT LV RO

(30) Priority: 17.06.1997 US 877050

(71) Applicant: SCHERING CORPORATION
KenilworthNew Jersey 07033 (US)

(72) Inventors:
  • NJOROGE, F., George
    Union, NJ 07083 (US)
  • VIBULBHAN, Bancha
    Kenilworth, NJ 07033 (US)
  • TAVERAS, Arthur, G.
    Rockaway, NJ 07866 (US)
  • DOLL, Ronald, J.
    Maplewood, NJ 07040 (US)
  • GIRIJAVALLABHAN, Viyyoor, M.
    Parsippany, NJ 07054 (US)

(74) Representative: Ritter, Stephen David et al
Mathys & Squire100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) NOVEL TRICYCLIC SULFONAMIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE