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(11)

EP 0 989 984 A1

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(43) Date of publication: 05.04.2000 Bulletin 2000/14 (21) Application number: 98928887.3 (22) Date of filing: 15.06.1998

(51) International Patent Classification (IPC)7: C07D 401/14, A61K 31/55, C07D 401/04, A61K 31/495, A61K 31/44 // (C07D401/14, 241:00, 221:00), C07D213:00 (86) International application number: PCT/US9811/496 (87) International publication number: WO 9857/961 (23.12.1998 Gazette 1998/51)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: LT LV RO (30) Priority: 17.06.1997 US 877743 (71) Applicant: SCHERING CORPORATION KenilworthNew Jersey 07033 (US)	(72) Inventors: COOPER, Alan, B. West Caldwell, NJ 07006 (US) DESAI, Jagdish, A. Spotswood, NJ 08884 (US) SAKSENA, Anil, K. Upper Montclair, NJ 07043 (US) GIRIJAVALLABHAN, Viyyoor, M. Parsippany, NJ 07054 (US) WANG, James, J.-S. Westfield, NJ 07090 (US) (74) Representative: Ritter, Stephen David et al Mathys & Squire100 Grays Inn Road London WC1X 8AL London WC1X 8AL (GB)