TRANSCRIPTIONAL ACTIVATORS WITH GRADED TRANSACTIVATION POTENTIAL

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EP 0 990 030 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	12.05.2010 Bulletin 2010/19

(45)	Mention of the grant of the patent:
	03.03.2010 Bulletin 2010/09

(21)	Application number: 98931801.9

(22)	Date of filing: 01.07.1998

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International Patent Classification (IPC):

C12N 15/00^(2006.01)
C12N 15/62^(2006.01)
C12N 15/67^(2006.01)
C12N 5/10^(2006.01)
C12Q 1/68^(2006.01)
A61K 48/00^(2006.01)

C12N 15/38^(2006.01)
C12N 15/63^(2006.01)
C12N 15/85^(2006.01)
C07K 14/035^(2006.01)
A01K 67/027^(2006.01)

(86)	International application number:
	PCT/US1998/013993

(87)	International publication number:
	WO 1999/001549 (14.01.1999 Gazette 1999/02)

(54)	TRANSCRIPTIONAL ACTIVATORS WITH GRADED TRANSACTIVATION POTENTIAL TRANSSKRIPTIONSAKTIVATOREN MIT STUFENWEISEN TRANSAKTIVIERENDEM POTENTIAL ACTIVATEURS DE TRANSCRIPTION AVEC UN POTENTIEL DE TRANSACTIVATION PROGRESSIF

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

03.07.1997 US 888080

(43)	Date of publication of application:
	05.04.2000 Bulletin 2000/14

(60)	Divisional application:
	08168539.8 / 2050818

(73)	Proprietor: TET Systems Holding GmbH & Co. KG
	69120 Heidelberg (DE)

(72)	Inventors:
	BARON, Udo D-10245 Berlin (DE) GOSSEN, Manfred El Cerrito, CA 94530 (US) BUJARD, Hermann D-69120 Heidelberg (DE)

(74)	Representative: Stößel, Matthias et al
	Herzog Fiesser & Partner Bad Kreuznacher Straße 27-29 68309 Mannheim 68309 Mannheim (DE)

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References cited: :

WO-A-92/02251
WO-A-96/01313
WO-A-97/30164

WO-A-94/29442
WO-A-96/40892
US-A- 5 464 758

BUJARD H ET AL: "Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential." NUCLEIC ACIDS RESEARCH, (1997 JUL 15) 25 (14) 2723-9. JOURNAL CODE: O8L. ISSN: 0305-1048., XP002080375

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).