(19)
(11) EP 0 993 318 A1

(12)

(43) Date of publication:
19.04.2000 Bulletin 2000/16

(21) Application number: 98938676.8

(22) Date of filing: 30.06.1998
(51) International Patent Classification (IPC)7A61N 1/32
(86) International application number:
PCT/EP9803/976
(87) International publication number:
WO 9901/175 (14.01.1999 Gazette 1999/02)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
SI

(30) Priority: 30.06.1997 FR 9708233
30.06.1997 FR 9708232
01.12.1997 US 67488 P
01.12.1997 US 67487 P
01.05.1998 US 83858 P

(71) Applicants:
  • RHONE-POULENC RORER S.A.
    92160 Antony (FR)
  • INSTITUT GUSTAVE ROUSSY
    F-94805 Villejuif Cédex (FR)
  • CENTRE NATIONAL DELA RECHERCHE SCIENTIFIQUE (CNRS)
    75016 Paris (FR)

(72) Inventors:
  • BUREAU, Michel
    F-92210 Saint Cloud (FR)
  • MIR, Lluis
    F-91370 Verrières Le Buisson (FR)
  • SCHERMAN, Daniel
    F-75012 Paris (FR)
  • SCHWARTZ, Bertrand
    F-94700 Maisons Alfort (FR)

(74) Representative: Bouvet, Philippe 
Rhône-Poulenc Rorer S.A.20, Avenue Raymond Aron
92160 Antony
92160 Antony (FR)

   


(54) DEVICE FOR OPTIMIZED ELECTROTRANSFER OF NUCLEIC ACID VECTORS TO TISSUES IN VIVO