(19)
(11) EP 0 993 448 A1

(12)

(43) Date of publication:
19.04.2000 Bulletin 2000/16

(21) Application number: 98930362.3

(22) Date of filing: 18.06.1998
(51) International Patent Classification (IPC)7C07D 213/79, A61K 31/44
(86) International application number:
PCT/US9812/682
(87) International publication number:
WO 9857/934 (23.12.1998 Gazette 1998/51)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE LI LU NL PT SE

(30) Priority: 19.06.1997 US 878562

(71) Applicant: THE DU PONT MERCK PHARMACEUTICAL COMPANY
Wilmington,Delaware 19898 (US)

(72) Inventors:
  • PRUITT, James, Russell
    Landenberg, PA 19350 (US)
  • PINTO, Donald, Joseph, Phillip
    Newark, DE 19702 (US)
  • QUAN, Mimi, Lifen
    Newark, DE 19711 (US)
  • WEXLER, Ruth, Richmond
    Wilmington, DE 19810 (US)

(74) Representative: Pett, Christopher Phineas et al
Frank B. Dehn & Co.,European Patent Attorneys,179 Queen Victoria Street
London EC4V 4EL
London EC4V 4EL (GB)

   


(54) (AMIDINO)6-MEMBERED AROMATICS AS FACTOR Xa INHIBITORS