(19)
(11) EP 0 994 953 A1

(12)

(43) Date of publication:
26.04.2000 Bulletin 2000/17

(21) Application number: 98929103.4

(22) Date of filing: 19.06.1998
(51) International Patent Classification (IPC)7C12N 15/62, C12N 15/69, C12N 15/85, C12N 5/10, C07K 14/72, C07K 14/025
// A61K48:00
(86) International application number:
PCT/US9812/777
(87) International publication number:
WO 9859/059 (30.12.1998 Gazette 1998/52)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 20.06.1997 US 50356 P

(71) Applicant: CASE WESTERN RESERVE UNIVERSITY
Cleveland, OH 44106-4984 (US)

(72) Inventors:
  • COOPER, Mark, J.
    Cleveland, OH 44106-3052 (US)
  • BRUNOVSKI, Peter
    Cleveland, OH 44106-3052 (US)

(74) Representative: Dean, John Paul et al
Withers & Rogers,Goldings House,2 Hays Lane
London SE1 2HW
London SE1 2HW (GB)

   


(54) EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS