(19)
(11) EP 0 998 294 A1

(12)

(43) Date of publication:
10.05.2000 Bulletin 2000/19

(21) Application number: 98922465.4

(22) Date of filing: 22.05.1998
(51) International Patent Classification (IPC)7: A61K 31/70
(86) International application number:
PCT/US9810/390
(87) International publication number:
WO 9852/577 (26.11.1998 Gazette 1998/47)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 22.05.1997 US 47430 P

(71) Applicant: CASE WESTERN RESERVE UNIVERSITY
Cleveland, OH 44106-4984 (US)

(72) Inventors:
  • MILLER, Robert, H.
    Cleveland Heights, OH 44106 (US)
  • NOLL, Elizabeth
    Brookline, MA 02146 (US)
  • NAKASUJI, Yuji
    Cleveland Heights, OH 44106 (US)
  • BLACK, Peter, McLaren
    Boston, MA 02108 (US)

(74) Representative: Kador & Partner 
Corneliusstrasse 15
80469 München
80469 München (DE)

   


(54) GANGLIOSIDE GM3 INDUCED APOPTOSIS OF NEURAL CELLS