(19)

(11)

EP 0 998 561 A1

(12)

(43) Date of publication: 10.05.2000 Bulletin 2000/19 (21) Application number: 98934441.1 (22) Date of filing: 10.07.1998

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 15/62, C07K 14/715, C07K 16/28, C07K 16/46, A61K 38/17 (86) International application number: PCT/US9814/410 (87) International publication number: WO 9903/992 (28.01.1999 Gazette 1999/04)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 15.07.1997 US 892119 (71) Applicant: Immunex CorporatioN Seattle, WA 98101 (US)	(72) Inventor: DEGLI-ESPOSTI, Mariapia Perth, W.A. 6148 (AU) (74) Representative: Cornish, Kristina Victoria Joy et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)