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(11)

EP 0 998 562 A1

(12)

(43) Date of publication: 10.05.2000 Bulletin 2000/19 (21) Application number: 98935206.7 (22) Date of filing: 23.07.1998

(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/705 (86) International application number: PCT/GB9802/207 (87) International publication number: WO 9905/271 (04.02.1999 Gazette 1999/05)

(84) Designated Contracting States: AT BE CH DE ES FI FR GB IE IT LI (30) Priority: 23.07.1997 GB 9715387 (71) Applicants: Gould, Hannah Jane London WC2B 5RL (GB) Sutton, Brian John London WC2B 5RL (GB)	(72) Inventors: Gould, Hannah Jane London WC2B 5RL (GB) Sutton, Brian John London WC2B 5RL (GB) (74) Representative: Lucas, Brian Ronald et al Lucas & Co.135 Westhall Road WarlinghamSurrey CR6 9HJ WarlinghamSurrey CR6 9HJ (GB)