(19)

(11)

EP 1 000 017 A1

(12)

(43) Date of publication: 17.05.2000 Bulletin 2000/20 (21) Application number: 98938138.9 (22) Date of filing: 29.07.1998

(51) International Patent Classification (IPC)7: C07C 241/00 (86) International application number: PCT/US9815/830 (87) International publication number: WO 9906/354 (11.02.1999 Gazette 1999/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: SI (30) Priority: 29.07.1997 US 54001 P (71) Applicant: SMITHKLINE BEECHAM CORPORATION PhiladelphiaPennsylvania 19103 (US)	(72) Inventor: WIDDOWSON, Katherine, L. King of Prussia, PA 19406 (US) (74) Representative: Blakey, Alison Jane et al Smithkline Beecham,Corporate Intellectual Property,Two New Horizons Court Brentford,Middlesex, TW8 9EP Brentford,Middlesex, TW8 9EP (GB)