(19)
(11) EP 1 000 054 A1

(12)

(43) Date of publication:
17.05.2000 Bulletin 2000/20

(21) Application number: 98939643.7

(22) Date of filing: 28.07.1998
(51) International Patent Classification (IPC)7: C07D 333/24, C07D 409/14, A61K 31/38, A61K 31/405
(86) International application number:
PCT/EP9804/705
(87) International publication number:
WO 9906/393 (11.02.1999 Gazette 1999/06)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.07.1997 EP 97113191

(71) Applicant: Roche Diagnostics GmbH
68298 Mannheim (DE)

(72) Inventors:
  • DI DOMENICO, Roberto
    I-20127 Milano (IT)
  • DE CILLIS, Gianpiero
    I-20056 Trezzo Sull'Adda (IT)
  • KÖNIG, Bernhard
    D-82335 Berg (DE)
  • ZIMMERMANN, Gerd
    D-68309 Mannheim (DE)

(74) Representative: Weber, Manfred, Dr. 
Roche Diagnostics GmbHPatent Department Pharma(TR-E)Sandhofer Strasse 116
68298 Mannheim
68298 Mannheim (DE)

   


(54) OLIGO-THIOPHENES USEFUL AS ANTIMETASTATIC AGENTS, A PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM