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(11)

EP 1 000 141 A1

(12)

(43) Date of publication: 17.05.2000 Bulletin 2000/20 (21) Application number: 98904362.5 (22) Date of filing: 26.02.1998

(51) International Patent Classification (IPC)7: C12N 15/10, C12Q 1/68, C12N 15/66 (86) International application number: PCT/IL9800/094 (87) International publication number: WO 9838/296 (03.09.1998 Gazette 1998/35)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 27.02.1997 IL 12033797 (71) Applicant: Gesher-Israel Advanced Biotecs (1996) Ltd. 90830 Bet Neqofa (IL)	(72) Inventor: SHARON, Gil 90805 Mevasseret Zion (IL) (74) Representative: Böhm, Brigitte, Dipl.-Chem. Dr. et al PatentanwälteWeickmann & PartnerPostfach 86 08 20 81635 München 81635 München (DE)