(19)
(11) EP 1 001 972 A1

(12)

(43) Date of publication:
24.05.2000 Bulletin 2000/21

(21) Application number: 98937990.4

(22) Date of filing: 30.07.1998
(51) International Patent Classification (IPC)7C07K 5/062, C07K 5/065, C07K 5/078, A61K 38/05
(86) International application number:
PCT/US9815/313
(87) International publication number:
WO 9906/431 (11.02.1999 Gazette 1999/06)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.07.1997 US 920394

(71) Applicants:
  • Elan Pharmaceuticals, Inc.
    South San Francisco, CA 94080 (US)
  • AMERICAN HOME PRODUCTS CORPORATION
    Madison, New Jersey 07940-0874 (US)

(72) Inventors:
  • THORSETT, Eugene, D.
    Moss Beach, CA 94038 (US)
  • SEMKO, Christopher, M.
    Fremont, CA 94539 (US)
  • SARANTAKIS, Dimitrios
    Newtown, PA 18940 (US)
  • PLEISS, Michael, A.
    Sunnyvale, CA 94087 (US)
  • LOMBARDO, Louis, John
    Belle Mead, NJ 08502 (US)
  • KREFT, Anthony
    Langhorne, PA 19047 (US)
  • KONRADI, Andrei, W.
    San Francisco, CA 94123 (US)
  • GRANT, Francine, S.
    San Francisco, CA 94118 (US)
  • DRESSEN, Darren, B.
    San Mateo, CA 94403 (US)
  • DAPPEN, Michael, S.
    Redwood City, CA 94061 (US)
  • BAUDY, Reinhardt, Bernhard
    Doylestown, PA 18901 (US)
  • ASHWELL, Susan
    Plainsboro, NJ 08536 (US)

(74) Representative: Adams, Nicola et al
Abel & Imray,20 Red Lion Street
London WC1R 4PQ
London WC1R 4PQ (GB)

   


(54) SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4